Reprocessing flexible endoscopes in today’s fast-paced clinical environment demands consistent, effective high-level disinfection (HLD) using automated endoscope reprocessors (AERs). Yet, despite advancements in technology over the last decade, AER operators are still required to manually test biocide minimum recommended concentration (MRC) levels during every cycle using a test strip. With the introduction of the ASP AEROFLEX™ AER with AUTOSURE™ MRC Monitor, automatic MRC testing for every cycle is a standard feature, designed to increase compliance and patient safety and reduce the risk of healthcare-acquired infections during endoscopy procedures. The AUTOSURE™ MRC Monitor is a novel automated concentration measurement system grounded in mature chemistry and colorimetry; a summary technical explanation is presented in this document.